| CASE REPORT |
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| Year : 2023 | Volume
: 13
| Issue : 1 | Page : 40-42 |
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Congenital cardiac surgery in a patient with cold agglutinins
Mridul Agarwal, Reena Khantwal Joshi, Neeraj Aggarwal, Raja Joshi
Department of Pediatric Cardiac Sciences, Sir Ganaga Ram Hospital, New Delhi, India
Correspondence Address:
Dr. Mridul Agarwal
F-57, Sir Ganga Ram Hospital, Rajender Nagar, New Delhi - 110 060
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/cmrp.cmrp_73_21
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Cold agglutinin disease is a type of autoimmune haemolytic anaemia caused by autoantibodies that bind to red blood cell antigens at a cold temperature and causes extravascular haemolysis and sometimes thrombosis also. Due to exposure to a lower temperature during open-heart surgery, the activation of haemolysis may occur in the presence of cold agglutinin antibodies. We present the management of a cyanotic child who has undergone open-heart surgery after the detection of high cold agglutinin titres during routine pre-transfusion screening.
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