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Year : 2023  |  Volume : 13  |  Issue : 1  |  Page : 40-42

Congenital cardiac surgery in a patient with cold agglutinins

Department of Pediatric Cardiac Sciences, Sir Ganaga Ram Hospital, New Delhi, India

Correspondence Address:
Dr. Mridul Agarwal
F-57, Sir Ganga Ram Hospital, Rajender Nagar, New Delhi - 110 060
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/cmrp.cmrp_73_21

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Cold agglutinin disease is a type of autoimmune haemolytic anaemia caused by autoantibodies that bind to red blood cell antigens at a cold temperature and causes extravascular haemolysis and sometimes thrombosis also. Due to exposure to a lower temperature during open-heart surgery, the activation of haemolysis may occur in the presence of cold agglutinin antibodies. We present the management of a cyanotic child who has undergone open-heart surgery after the detection of high cold agglutinin titres during routine pre-transfusion screening.

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